Day 1 – Friday, 5 November 2021
| 14:00-14:10 | Opening |
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| 14:10-15:20 | Plenary session Congress Hall Chair: József Mihály |
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| 14:10-14:45 | PL-1 Imre Kacskovics Development of a recombinant ACE2-Fc fusion protein as a potential drug against SARS-CoV-2 |
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| 14:45-15:20 | PL-2 Beáta Lontay New quarterback in the field of insulin resistance |
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| 15:20-15:45 | Bioscience award talk |
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| 15:20-15:45 | BA Ádám Póti Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents |
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| 15:45-16:15 | Company talks |
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| 15:45-16:00 | Zeiss Chris Power (Carl Zeiss, Cambridge, United Kingdom) Overview of recent advances in optical sectioning microcopy at Carl Zeiss |
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| 16:00-16:15 | Kvalitex Kristin Schnettler (NEW ENGLAND BIOLABS) How to build a streamlined, easy scalable and multi-functional DNA & RNA NGS Library prep pipeline |
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| 16:15-17:00 | Coffee break |
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| 17:00-18:35 | Molecular mechanism of diseases I. Congress Hall Chair: Zsuzsa Szondy |
Protein structure & function Room Liget I. Chair: László Nyitray |
| 17:00-17:20 | O-01 Zsuzsanna Izsvak PiggyBac Transposable Element-derived 1, unique to mammals, controls Neuronal Progenitor Identity, Stress Sensing and mammal-specific paraspeckles |
O-07 Zoltán Lipinszki Novel Perspectives of Target-binding by the Evolutionarily Conserved PP4 Phosphatase |
| 17:20-17:35 | O-02 András Szabó Defective binding of SPINK1 variants is an uncommon mechanism for impaired trypsin inhibition in chronic pancreatitis |
O-08 Kinga Nyiri Investigation of Protein and Peptide type Inhibitors of the Human dUTPase |
| 17:35-17:50 | O-03 Tamás Arányi The pathogenic p.R391G ABCC6 displays incomplete penetrance implying the necessity of an interacting partner for the development of pseudoxanthoma elasticum |
O-09 Zoltán Gáspári Dynamic ensembles highlight unique features of the PDZ domains of PSD-95 |
| 17:50-18:05 | O-04 Andrea Kelemen IFITM1 expression determines extracellular vesicle uptake in colorectal cancer |
O-10 Beáta Longauer Effect of A22 and nucleotides on MreB polymerisation |
| 18:05-18:20 | O-05 Andrea Ciliberto Epistasis, aneuploidy, and functional mutations underlie the evolution of resistance to induced microtubule depolymerization |
O-11 Tamás Hegedűs Transmembrane protein structure prediction by AlphaFold2 |
| 18:20-18:35 | O-06 Zoltán Wiener WNT Activity And Cell Proliferation are Coupled to Extracellular Vesicle Release in Lung Cancer Organoid Models |
O-12 Ágnes Tantos RNA binding of SETD1A and SETD1B |
| 18:45-20:15 | Welcome dinner | |
| 20:15-22:00 | Poster discussion with drinks – ODD number posters Jump to List of posters Proteomics Clinique |
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Day 2 – Saturday, 6 November 2021
| 09:00-10:35 | Molecular mechanism of diseases II. Congress Hall Chair: Gábor Szabó |
Developmental Genetics Room Liget I. Chair: Rita Sinka |
| 09:00-09:20 | O-13 Bálint Bálint Machine-learning based method to predict endometroid grade and relapse risk from global gene expression datasets |
O-18 Gábor Csordás Immune cell redirection reveals the underlying mechanisms of hematopoietic tissue formation in Drosophila |
| 09:20-09:35 | O-14 Éva Csősz Amino acids and biogenic amines as indicators of altered metabolic fluxes in obesity and diabetes |
O-19 Péter Borkúti The biological significance of nuclear actin |
| 09:35-09:50 | O-15 Krisztina Tar The diverse functions of the proteasome activator PA200 to maintain cellular quality control. |
O-20 István Földi Role of formin proteins in the cytoskeleton coordination during axonal growth |
| 09:50-10:05 | O-16 Endre Kristóf Irisin stimulates the release of CXCL1 from human subcutaneous and deep-neck derived adipocytes |
O-21 Elham Alzyoud Microtubule organizing centers contain testis-specific γ-TuRC proteins in spermatids of Drosophila |
| 10:05-10:20 | O-17 Iván Uray Dissecting drug interactions utilizing rexinoid and G-protein-coupled receptors for cancer prevention |
O-22 Áron Szabó LC3-associated Phagocytosis Promotes Glial Degradation of Axon Debris after Injury |
| 10:20-11:05 | Coffee break |
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| 11:05-12:40 | Genome manipulation & archeogenetics Congress Hall Chair: Zoltán Ivics |
Cell differentiation and signaling Room Liget I. Chair: László Buday |
| 11:05-11:25 | O-23 Zoltán Ivics Engineered Sleeping Beauty Transposase Redirects Transposon Integration Away from Genes |
O-29 Zsolt Sarang Impaired Skeletal Muscle Development and Regeneration in Transglutaminase 2 Knockout Mice |
| 11:25-11:40 | O-24 András Tálas BEAR reveals that increased fidelity variants can successfully reduce the mismatch-tolerance of adenine but not cytosine base editors |
O-30 Erika Gábor Elucidating the Regulation of Hemocyte Transdifferentiation with a Complex Deep Learning Based Technology In Drosophila Melanogaster |
| 11:40-11:55 | O-25 Péter István Kulcsár How to choose the most suitable increased fidelity SpCas9 nuclease for high specificity genome editing |
O-31 Milán Somogyvári The sirtuin ortholog SIR-2.1 regulates lipolysis via the heat shock factor HSF-1 in C. elegans |
| 11:55-12:10 | O-26 Dániel Gerber Genetic history and life of Bronze Age communities in Western Hungary |
O-32 Anita Kurilla Identification of oncogene-specific Tks4-Binding Protein Complexes as Biomarker Panels for Various Cancers |
| 12:10-12:25 | O-27 Bea Szeifert Chapters from Carpathian Basin’s Early Medieval genetic history |
O-33 Fadi Ramadan Involvement of Mitochondrial Mechanisms in the Cytostatic Effect of Desethylamiodarone in B16f10 Melanoma Cells |
| 12:25-12:40 | O-28 Tibor Török Population Genoimc Characterization of Migration Period Populations in the Carpathian Basin |
O-34 Károly Jambrovics Role of transglutaminase 2 (TG2) in the differentiation and apoptotic processes of all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) treated NB4 leukaemia cell lines |
| 12:40-14:10 | Lunch |
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| 14:10-15:20 | Plenary session Congress Hall Chair: Mihály Kovács |
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| 14:10-14:45 | PL-3 László Nagy Evolution repeats itself in fungal morphogenetic transitions - in search of mechanisms of convergent evolution |
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| 14:45-15:20 | PL-4 János Réthelyi CRISPR genome editing based isogenic induced pluripotent stem cell system for modeling ZMYND11 de novo mutation in schizophrenia |
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| 15:20-15:35 | Company talks |
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| 15:20-15:35 | BioVendor dr. Klára Lakatoš (BioVendor – MDX a.s.) Library in three hours - NGS kits from BioVendor |
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| 15:35-15:40 | Technical break |
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| 15:40-16:45 | Drug development Congress Hall Chair: László Virág |
Stem cells Room Liget I. Chair: András Nagy |
| 15:40-16:00 | O-35 László Virág High-Content Screening For Drug Development |
O-39 András Nagy Combining gene and cell therapy offers “universal” cells to treat disease |
| 16:00-16:15 | O-36 Csilla Laczka Fluorescent probes of Organic Anion Transporting Polypeptides (OATPs), transporters involved in drug ADME-Tox |
O-40 Kornélia Szebényi Human ALS/FTD Brain Organoid Slice Cultures Display Distinct Early Astrocyte and Targetable Neuronal Pathology |
| 16:15-16:30 | O-37 Máté Lengyel Targeting serotonergic signaling as a potential growth control pathway in breast cells |
O-41 Tünde Szatmári Ionizing radiation differentially affects the uptake of extracellular vesicles by bone marrow cell subpopulations |
| 16:30-16:45 | O-38 András Füredi Switching off Drug Resistance in Cancer |
O-42 István Szatmári Zbtb46 dependent altered developmental program in embryonic stem cell derived blood cell progenitors: improved erythropoiesis and diminished myelopoiesis |
| 16:45-19:00 | Poster discussion with coffee break, EVEN number posters Jump to Poster session Proteomics Clinique |
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| 20:00- | Banquet | |
Day 3 – Sunday, 7 November 2021
| 09:30-11:05 | DNA repair and carcinogenesis Congress Hall Chair: Dávid Szüts |
Session epigenetics & regulation of gene expression Room Liget I. Chair: Tamás Arányi |
| 09:30-09:50 | O-43 Mihály Kovács Liquid-liquid phase separation driven by ssDNA binding protein enables rapid and efficient genome repair |
O-49 Tibor Pankotai Transcriptional changes in response to DNA damage |
| 09:50-10:05 | O-44 Péter Burkovics The role of human WRNIP1 protein in genome maintenance |
O-50 László Imre Fundamental Role of The H2A.Z C-terminal Tail in The Formation of Constitutive Heterochromatin |
| 10:05-10:20 | O-45 Lóránt Székvölgyi Chromatin architectural changes set the stage for meiotic DNA break formation |
O-51 Ildikó Kristó Moesin is involved in mRNA export as a new member of the Mediator complex |
| 10:20-10:35 | O-46 Éva Bálint Functional significance of the Rad18 Zn-finger mediated interaction with Rad5 |
O-52 Maher Alnajjar Combined RNA-seq and WGS analysis of a rabbit family reveals clear genotype supported intermediate inheritance of gene expression levels at many genes |
| 10:35-10:50 | O-47 Gábor Szabó Regulation of nucleosome stability: the roles of histone PTMs, histone variant composition and superhelicity |
O-53 Melinda Bence Initiation of Piwi Mediated Heterochromatin Formation in Drosophila Melanogaster |
| 10:50-11:05 | O-48 Gyula Timinszky PARP inhibitors and the molecular mechanisms underlying their PARP1 trapping activity |
O-54 Melinda Pirity Polycomb protein RYBP associates with cardiac transcription factor NKX2-5 to regulate Plagl1 during in vitro cardiac differentiation of mouse embryonic stem cells |
| 11:05-11:40 | Coffee break | |
| 11:40-12:55 | Plant Biology & Regulatory RNA Congress Hall Chair: László Szabados |
Autophagy and i.c. trafficking Room Liget I. Chair: Tibor Vellai |
| 11:40-11:55 | O-55 László Szabados Proline metabolism acts as regulatory hub in higher plants |
O-60 Tamás Csizmadia The role of ubiquitin in the secretory granule degradation in Drosophila |
| 11:55-12:10 | O-56 Renáta Hamar The zebrafish snoRNAome |
O-61 Endre Kókai Cathepsin D interacts with the adenosine A2A receptors in mouse macrophages establishing a mutual molecular and functional regulation |
| 12:10-12:25 | O-57 Anita Sós-Hegedűs Molecular Analysis of Tomato Shoestring Symptom |
O-62 Sarolta Tóth Plasmamembrane calcium pump PMCA4b is a new regulator of lumen formation and secretion |
| 12:25-12:40 | O-58 Anna Anita Rácz Small RNA sequencing reveals specific microRNA signatures due to invasive aspergillosis in oncohematology patients |
O-63 Gábor Hajdú Lysosome-related organelles are required for toxic stress-induced cytoprotective and immune responses in C. elegans |
| 12:40-12:55 | O-59 Anikó Zeöld miRNA profiling of extracellular vesicles from pancreatic ductal adenocarcinoma patient-derived organoids and blood |
O-64 László Homolya Theratype-based classification of medically important mutations in the ABCG2 multidrug transporter |
| 13:00-13:15 | Closing and award ceremony Congress Hall |
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| 13:15- | Lunch | |
Proteomics Clinique
Do you have questions related to proteomics? Are you unsure which method to choose or how to submit a sample? If you would you like to get first-hand information from specialists, come and visit the Proteomics Clinique. At our booth, we would like to give researchers and students a possibility to ask questions about the complete proteomics analysis workflow starting from experimental design, method selection, sample preparation, sample submission to data analysis and data interpretation during Poster sessions in Room Liget I. Experienced researchers working at the proteomics core facilities in Szeged and Debrecen will answer the questions and will give tips on how you can get out more from your proteomics analyses.
List of posters - 5-6 November 2021
| P-001 | Marianna Holczer The systems biological analysis of PP2A-ULK1-mTORC1 regulatory triangle | |
| P-002 | Zoltán Kovács Nuclear import dynamics of the Drosophila moesin protein | |
| P-003 | Tibor Kovács Autophagy is required for spermatogonial differentiation in the Drosophila testis | |
| P-004 | Hussein Abu Ammar Role of lysoosmal Trpml/mucolipin-1 calcium channel in starvaton-induced autophagy | |
| P-005 | Asha kiran Maddali Lipid profiles of autophagic structures isolated from wild type and Atg2 mutant Drosophila | |
| P-006 | Dávid Hargitai Characterization of the endolysosomal SNARE proteins in Drosophila melanogaster | |
| P-007 | Anna Dósa The role of E3 ubiquitin ligases in the regulation of crinophagy | |
| P-008 | Adél Ürmösi Analyzing the importance the loss of ubiquitinated protein autophagy due to a mutation in Ref(2)P/p62 in Drosophila | |
| P-009 | Tamás Maruzs Exploring Sorting nexin functions in Drosophila | |
| P-010 | Janka Szinyákovics A conserved MTMR lipid phosphatase increasingly suppresses autophagy in brain neurons during aging | |
| P-011 | Enikő Lakatos Investigation of the function of Snx21 in Drosophila melanogaster | |
| P-012 | Gábor Hajdú LRO-dependent stress and immune defenses require the pgp-2 ABC transporter in C. elegans | |
| P-013 | Dániel Kovács Age dependent hormetic response to HSF-1 depletion suggests a compensatory mechanism of cellular stress signaling in Caenorhabditis elegans | |
| P-014 | Ármin Sőth Identifying new protein interacting partners of EHD1 in the endosomal system | |
| P-015 | Zsófia Simon-Vecsei Investigation of the balance between human endolysosomal tethering complexes | |
| P-016 | LINA FADEL Agonist binding directs dynamic competition among nuclear receptors for heterodimerization with Retinoid X Receptor | |
| P-017 | Márk Kovács COMPARATIVE TRANSCRIPTOME ANALYSIS OF SACCHAROMONOSPORA AZUREA STRAINS IN TERMS OF PRIMYCIN PRODUCING ABILITY | |
| P-018 | Walliyulahi Ajibola Seeking novel antimicrobials derived from environmental bacteria | |
| P-019 | Erik Seitz Development of a new, intercellular network model of the epithelial-mesenchymal transition (EMT) | |
| P-020 | Máté Metzing Study of the 3D structures of mixed Saccharomyces cerevisiae colonies | |
| P-021 | János Juhász FITTING IN-SILICO YEAST COLONY GROWTH MODEL TO EXPERIMENTAL DATA | |
| P-022 | Bálint Biró Mitochondrial insertions in the rabbit nuclear genome | |
| P-023 | János Barna Prediction of gene function based on Caenorhabditis elegans operons | |
| P-024 | Nóra Görög Investigation of cell-cell interactions between industrial wine yeasts | |
| P-025 | Tünde Gaizer SYSTEM LEVEL INVESTIGATION OF YEAST CELL-CELL INTERACTIONS | |
| P-026 | Veronika Törökné Ács Revealing the role of different amino acid properties in the disordered flanking regions of linear motifs | |
| P-027 | Áron Bartha Discriminating malignant and healthy kidney tissues using proteomic and transcriptomic data | |
| P-028 | Dávid Keresztes Potential role of ISG15 and androgen receptor contact in enzalutamide resistance of prostate cancer | |
| P-029 | Patrik Kovács GLOBAL ANALYSIS OF EXPRESSION OF TRANSPORTERS IN CHONDROGENESIS | |
| P-030 | Csaba Pongor Development of High Throughput Methods to Study Yeast Colony Growth | |
| P-031 | Dalma Müller Analysis of DNA methylation associated with altered gene expression in colorectal cancer | |
| P-032 | Borbála Kovács Network Topological Reorganization of Signaling Networks In the Oncogenesis of Colon Cancer | |
| P-033 | Ádám Nagy Transcriptomic effect of APC mutations in colon adenocarcinoma | |
| P-034 | Péter Fauszt Investigating the dietary habits- and lifestyle-induced changes in gut microbiota composition and functionality by the application of shotgun next-generation sequencing | |
| P-035 | Bernadette Hotzi HSF1Base: A Comprehensive Database of HSF1 (Heat Shock Factor 1) Target Genes | |
| P-036 | Gábor Fidler Effect of geographical provenance on the antimicrobial resistance load of the human gastrointestinal tract | |
| P-037 | Bence Keömley-Horváth Predicting drug side-effects using whole-cell level protein complex simulations | |
| P-038 | Péter Dávid Investigation the influence of agronomic management on the vineyard soil, trunk-bark and grape berry microbiome of Vitis vinifera from Tokaj-Wine region and Pallag-Botanical and Exhibitional garden | |
| P-039 | Márk Kerestély Boolean modelling of protein translocations reveals compartment-specific perturbations altering the fate of epithelial-mesenchymal transition | |
| P-040 | János Tibor Fekete Random forest model to identify predictive genes in colorectal cancer samples | |
| P-041 | Otília Menyhart Potential druggable targets in VHL-mutant clear-cell renal cell carcinomas (ccRCC) | |
| P-042 | Szonja Kovács Predictive role of MLH1 (MutL Homolog 1) in malignant cancers treated with immunotherapy | |
| P-043 | András Szabó Charged residue repeats and their effects on liquid-liquid phase separation | |
| P-044 | Margita Ágnes Márton A systems biological analysis of ER stress-induced ATF4-GADD34-CHOP regulatory triangle | |
| P-045 | Viktor Dombradi MEMBRANE-FUNCTIONS OF THE FUNGUS SPECIFIC PROTEIN PHOSPHATASE Z1 | |
| P-046 | Renáta Gáspár Kynurenic acid exerts antiapoptotic effects against simulated ischemia/reperfusion injury on H9c2 cells | |
| P-047 | Zsuzsa Szondy TAM KINASE SIGNALING IS INDISPENSABLE FOR PROPER SKELETAL MUSCLE REGENERATION IN MICE | |
| P-048 | Csaba Matta SYNCHRONISING THE CIRCADIAN CLOCK WITH MECHANICAL STIMULI DURING IN VITRO CHONDROGENESIS | |
| P-049 | Enikő Jávor-Hocsák Regulation of the ATF4-MKP-1-MAPK-mitochondrial damage-cell death pathway by PARP-1 in oxidative stress | |
| P-050 | Nour Al Zaeed Impaired Skeletal Muscle Development and Regeneration in Transglutaminase 2 Knockout Mice | |
| P-051 | Enikő Sutus Novel blood cell culturing method underlines leukocyte plasticity in Drosophila melanogaster | |
| P-052 | Dóra Halmi The role of mitoprotection in the cytoprotective effect of kynurenic acid against simulated ischemia/reoxygenation-induced cardiac cell damage | |
| P-053 | Aliz Géczi A machine learning based approach to identify blood cell fates in Drosophila melanogaster | |
| P-054 | Eliza Guti The receptor tyrosine kinase inhibitor sunitinib confers resistance to breast carcinoma cells from natural killer cell-mediated ADCC | |
| P-055 | Isotta Sturniolo A TUMOR SPHEROID MODEL TO INVESTIGATE THE INTERACTION BETWEEN MACROPHAGES AND CANCER CELLS | |
| P-056 | Marvi Ghani Effect of depletion of Drp1 and PA200 on neuronal differentiation and mutant huntingtin (mHtt) aggregate formation | |
| P-057 | Nastaran Tarban ROLE OF RETINOL SATURASE ENZYME IN SKELETAL MUSCLE REGENERATION | |
| P-058 | Kinga Fedor-Lénárt Tissue transglutaminase knock-out preadipocytes and beige cells of epidydimal fat origin possess decreased mitochondrial functions required for thermogenesis | |
| P-059 | Mevan Jacksi The role of Ezh2 and Tks4 in EMT-related processes | |
| P-060 | Julianna Lilienberg Pharmacological modulation of neurite outgrowth in human neural progenitor cells by inhibiting non-muscle myosin II | |
| P-061 | János Sónyák The role of PMCA4b in mammosphere formation and secretion in 3D cell cultures of MCF7 cells | |
| P-062 | Alexandra Brigitta Szarka-Kovács Mesr4: A novel positive regulator of germline differentiation | |
| P-063 | Abhirup Shaw BMP7 upregulates both UCP1 dependent and independent thermogenesis in human neck area derived adipocytes | |
| P-064 | Ákos Bordás Optimization of non-dividing cell selection in induced pluripotent stem cell-derived hepatic culture | |
| P-065 | László Sós Palmitate inhibits efferocytosis by activating the mTORc1/RhoA/Rho kinase pathway | |
| P-066 | Éva Péntek-Garabuczi NURR77 INHIBITS PHAGOCYTOSIS OF APOPTOTIC CELLS BY DOWNREGULATING PPARg | |
| P-067 | Éva Vincze-Fige RETINOIDS PROMOTE MACROPHAGE DIFFERENTIATION AND EFFEROCYTOSIS BY UPREGULATING BMP-2 | |
| P-068 | Viktória Zsiros Molecular control of mesenchymal-epithelial transformation after inflammation in mesothelial cells: the role of autophagy and BMP factors in the process | |
| P-069 | Virginia Varga Hemocytes influence cellular processes during the regeneration of germline cells in Drosophila testis | |
| P-070 | Péter Tóth CHIMERIC ANTIGEN RECEPTOR EXPRESSING MACROPHAGE CELLS (CAR-M) FOR THE THERAPY OF HER2+ SOLID TUMORS | |
| P-071 | Bianka Csaholczi Development and characterisation of a transglutaminase 2 knocked down endothelial cell model | |
| P-072 | Péter Görög FLIGHTLESS-I REGULATES SARCOMERE GROWTH BY PROMOTING ACTIN ASSEMBLY | |
| P-073 | Viktor Vedelek Mitochondrial dynamics and metabolic remodelling in Drosophila spermatogenesis | |
| P-074 | Bayan Kharrat HEADCASE AS A PLAYER IN STRESS RESPONSE IN THE HEMATOPOIETIC NICHE IN DROSOPHILA MELANOGASTER | |
| P-075 | Dávid Farkas SALS as a novel regulatory factor of sarcomeric growth | |
| P-076 | Krisztina Tóth THE ROLE OF FORMINS DURING DROSOPHILA EMBRYONIC DORSAL CLOSURE | |
| P-077 | Rita Gombos Drosophila Frl and Enabled work together to form actin cables for positioning nuclei during oogenesis | |
| P-078 | Roland Ádám Takács Identification of possible novel transcription factors during chondrogenic differentiation | |
| P-079 | László Henn How does the alternative linker histone ensure the earliest developmental steps in Drosophila? | |
| P-080 | Lili Adorján Emerging new role of RYBP and lncRNA Paupar in regulating Pax6 during neural differentiation | |
| P-081 | Zsanett Takács Analysis of a novel heterochromatin regulator in Drosophila Melanogaster | |
| P-082 | Lilla Kókity Mouse RYBP is important for cardiac mesoderm and progenitor formation in vitro | |
| P-083 | Latifa Kazzazy Uracil in the DNA during the early development of zebrafish | |
| P-084 | Eszter Németh Prospectively-defined patterns of APOBEC3A mutagenesis are prevalent in human cancers | |
| P-085 | Vasiliki Pantazi Ubiquitylation mediated transcription regulation upon DSB induction | |
| P-086 | Hasan Mamar The loss of the DNA polymerase epsilon subunits POLE3 and POLE4 results in PARP inhibitor sensitivity | |
| P-087 | János Pálinkás Pathways of D-loop processing by human Bloom’s syndrome helicase are markedly influenced by the Toposiomerase IIIalpha-RMI1-RMI2 complex | |
| P-088 | Gábor Papp Correlation between uracilation and transcriptional changes in drug treated HCT116 colon cancer cells. | |
| P-089 | Eszter Holub Induced C to T transition mutations in anticancer drug treated HCT116 cells | |
| P-090 | Angéla Békési Getting mechanistic insight into the action of thymidylate synthase inhibitory drugs | |
| P-091 | Szilvia Juhász The effect of G4 stabilization on genome integrity | |
| P-092 | Zita Bognár Desethylamiodarone may have cytostatic potential on triple negative breast cancer | |
| P-093 | Vikas Patel MOLECULAR ALTERATIONS ASSOCIATED WITH BRAFi/MEKi RESISTANCE IN MELANOMA CELL LINES | |
| P-094 | Stephanya Corral Identification of Microorganisms of Biotechnological Importance and their Characterization by Microbiological and Molecular Biological Approaches | |
| P-095 | Orsolya Ungvári A competitive counterflow assay to distinguish between substrates and inhibitors of the hepatic drug transporter OATP1B1 | |
| P-096 | Balázs Gombos Application of a transgenic mouse model for chemotherapy optimization | |
| P-097 | Eszter Bajtai CHARACTERIZATION OF CHEMOTHERAPY-SURVIVING TUMOR CELLS AND UNDERSTANDING THEIR ROLE IN RELAPSE | |
| P-098 | Nikoletta Murvai STUDY OF INHIBITION OF ALZHEIMER’S AMYLIOD-Β PEPTIDE AGGREGATION AND TOXICITY | |
| P-099 | Thu Hien Vu Biocides are unlikely to be a major source of antibiotic resistance | |
| P-100 | Rosevalentine Bosire ACCESSIBILITY OF DNA IN CHROMATIN: THE INFLUENCE OF CONSTRAINED SUPERHELICITY | |
| P-101 | Harem Muhamad Amin The RBR-polyQ Region Of KMT2D Enzyme: Unique Sequence-Specific Function | |
| P-102 | Ranti Dev Shukla inPOSE: an IS3 element-mediated and CRISPR/Cas9-assisted robust synthetic biology tool for transgene integration and amplification in bacterial genomes | |
| P-103 | Orsolya Mózner Examining the modulation of the plasma membrane calcium pump PMCA4b in erythroid cells | |
| P-104 | Márton Miskei Genome-wide mapping of SETMAR transposase binding sites in the human genome | |
| P-105 | Judit Vágó MODULATION OF DNA METHYLATION INFLUENCES CARTILAGE FORMATION IN MURINE CHONDROGENIC MODELS | |
| P-106 | Ferenc Jankovics Drosophila small ovary gene is required for transposon silencing and heterochromatin organization | |
| P-107 | Viola Varga The epigenetic role of ascorbate in the pathomechanism of arterial tortuosity syndrome | |
| P-108 | Ákos Avramucz Towards a T7/K1F chimera phage | |
| P-109 | Noémi Borbély Towards building the genetic map of the Carpathian Basin | |
| P-110 | Erzsébet Fóthi Similar or a little different? Two Hungarian-speaking populations in the Hungarian-Slavic contact zone | |
| P-111 | Dorottya Simon PEAR: a flexible fluorescent reporter for the identification and enrichment of successfully prime edited cells | |
| P-112 | Tímea Pintér INVESTIGATION OF DYSREGULATION OF GABA-GLUTAMATE SYSTEM IN DIP2C KNOCKOUT MOUSE MODEL | |
| P-113 | Henriett Halász Studying the role of the microtubules in the formation and function of the membrane nanotubes of B-lymphocytes | |
| P-114 | Éva Katona INVESTIGATION OF THE CIRCADIAN CLOCK GENES IN HUMAN MELANOMA CELLS | |
| P-115 | Ádám Diós Optimization of biosensor utilization for celiac disease related antibody quantification in BLItz system | |
| P-116 | András Áron Soós Wnt secretion is uncoupled from cell proliferation and extracellular vesicle release in human pancreatic ductal adenocarcinoma organoids | |
| P-117 | Loretta László Significance of Tks4 scaffold protein in embryonic stem cell differentiation: First steps in establishment of a new Tks4-KO HUES9 cells | |
| P-118 | Tamás Fehér Investigating a female-limited progressive myopia disease in a Hungarian family | |
| P-119 | Edit Szabó Potential diagnostic role of red blood cell membrane proteins in type 2 diabetes | |
| P-120 | Anna Kulin Investigation of factors behind the expression pattern of the GLUT1 membrane protein – potential relevance in diabetes | |
| P-121 | Ádám Ungvári Progesterone-dependent transcriptional programming provides smoothelin-like 1 reversal of insulin resistance in myotubes and mice | |
| P-122 | Zsófia Ruppert Sex-dependent effects of high-fat diet and HSPB1 overexpression in a mouse model of hyperlipidemia | |
| P-123 | Melinda Tóth Beneficial effects of regular exercise training on metabolic disturbances in ApoB100-overexpressing transgenic mice: sex-specific responses | |
| P-124 | Szilvia Blénesi The fear of hunger: starvation-induced aversive associative memory in C. elegans | |
| P-125 | Mihály Székely Protein arginine methyltransferase 5 in the pathomechanism of human lung cancer | |
| P-126 | Zsófia Nagy Investigation of the expression of dual oxidases in the gastrointestinal tract of cattle suffering from Left-Sided Displacement of the Abomasum | |
| P-127 | Brigitta Dukay Sex-dependent effects of regular exercise on cognitive function in healthy and hyperlipidemic mice | |
| P-128 | Rini Arianti ASC-1 transporter-dependent amino acid uptake is required for the efficient thermogenic response of human adipocytes to adrenergic stimulation | |
| P-129 | Boglárka Ágnes Vinnai Long-Term Thiamine Treatment Elevates Thermogenic Competency of Human Adipocytes | |
| P-130 | Ilka Keller The role of SMTNL-1 in the physiological and pathological functions of the female reproductive system | |
| P-131 | Vince Szegeczki Alterations of mRNA expression in PACAP treated in vitro ectopic endometrial tissues | |
| P-132 | Attila Vámos SYSTEMATIC ANALYSIS OF BEIGE TO WHITE TRANSITION OF HUMAN PRIMARY ADIPOCYTES | |
| P-133 | Diána Kaszás PMCA4b contributes to lumen formation and transcellular trafficking in the breast cancer MCF7 cell line | |
| P-134 | Gyöngyi Munkácsy PREDICTIVE ROLE OF MKI-67 AND PCNA CELL PROLIFERATION MARKERS IN THE PHARMACOLOGICAL TREATMENT OF BREAST CANCER | |
| P-135 | Réka Nagy Arf6 mediates endocytosis of PMCA4b in HEK cells | |
| P-136 | Tamás Juhász PAC1 receptor expression in aging of cartilage in human knee joints | |
| P-137 | Dávid Kis TYPES OF LEUKAEMIA IN RADIATION AND EXTRACELLULAR VESICLES INDUCED LEUKEMOGENESIS | |
| P-138 | Katalin Balázs Radiotherapy-induced changes in systemic immune parameters of prostate cancer patients | |
| P-139 | Péter Pikó The Profile of HDL-C Subfractions and Their Association with Cardiovascular Risk in the Hungarian General and Roma Population | |
| P-140 | István Szász Liquid biopsy-based biomarker identification in colorectal cancer | |
| P-141 | Dóra Csige Investigation of the conformational epitope of mouse monoclonal antibody 885 recognizing a celiac-related surface in transglutaminase 2 | |
| P-142 | Krisztina Köröskényi Loss of adenosine A3 signalling protects mice against diet-induced obesity | |
| P-143 | Tamás Molnár DISEASE RELATED D76N MUTATION OF Β2-MICROGLOBULIN: SYNERGY OF ADVERSE EFFECTS BOTH ON THE NATIVE AND AMYLOID STATES | |
| P-144 | Krisztina Jámbor Investigating osteopontin - a possible biomarker - in malignant melanoma cell lines in two levels | |
| P-145 | Francesco Desiderio Prunus virus F is present in Hungarian sour cherries | |
| P-146 | Evans Duah Agyemang Symptom on Clematis vitalba could be a reason for an infection with Prunus virus I | |
| P-147 | Roland Gábor Vékony INVESTIGATION OF THE ROLE OF THE NEUROPEPTIDE PACAP IN THE REGULATION OF THE CYTOSKELETAL SYSTEM | |
| P-148 | Gerda Wachtl Roles of the N-terminal Disordered Protein Region in PiggyBac transposition | |
| P-149 | Brigitta Maruzs NMR characterisation of the EVH1 domain of the postsynaptic Homer1 protein | |
| P-150 | Bálint Péterfia Natural point mutations of the PDZ domain affect ligand binding of the postsynaptic Shank1 protein | |
| P-151 | Balint Nagy Structure of the dihydrolipoamide succinyltransferase (E2) component of the human alpha-ketoglutarate dehydrogenase complex (hKGDHc) revealed by cryo-EM and cross-linking mass spectrometry: Implications for the overall hKGDHc structure | |
| P-152 | Eszter Nagy-Kanta NMR-based structural characterization of the post-synaptic density scaffold protein GKAP | |
| P-153 | Patrik Horváth In vitro interaction studies of chlorotoxin and its tumor-associated partners | |
| P-154 | András Czajlik Structural and Dynamical Investigation of Shank-1 PDZ domain | |
| P-155 | Péter Ecsédi Utilization of annexin A2 as a crystallization chaperon | |
| P-156 | Fanni Farkas Interaction and atomic level investigation of GBR region of GKAP and GK domain of PSD-95 | |
| P-157 | Beáta Bugyi Structural - Functional Analyses of the Gelsolin Homology Domains of Flightless-I in Actin Dynamics | |
| P-158 | Rawan Abukhairan RNA regulated phase Separation of KMT2D | |
| P-159 | Krisztina Veszelyi REDOX HOMEOSTASIS OF THE ENDOPLASMIC RETICULUM – ABSENT ELECTRON TRANSFER CHAINS IN THE LUMEN? | |
| P-160 | Beáta Szabó Disease causing mutations of KMT2D RNA binding domain affect its phase separation | |
| P-161 | Éva Schád Relationship between interfaces, binding strength and specificity of disordered protein complexes | |
| P-162 | Zsuzsánna Réthi-Nagy A NOVEL PROTEIN TAG FOR IMMUNODETECTION AND AFFINITY PURIFICATION OF PROTEINS | |
| P-163 | András Micsonai BeStSel: protein secondary structure estimation and fold recognition from CD spectra | |
| P-164 | Gergő Kalló Reduced level of tear antimicrobial and immunomodulatory proteins as a possible reason for higher ocular infections in diabetic patients | |
| P-165 | Erdenetsetseg Nokhoijav Complex examination of body fluids in diabetes and obesity | |
| P-166 | Andrea Guba Method development for simultaneous analysis of 33 amino acid and biogenic amine from serum and tears | |
| P-167 | Zsuzsa Csobán-Szabó An attempt to reveal the biological function of human transglutaminase 4 in the intestinal tract | |
| P-168 | Tibor Hajdú DISSECTING THE SURFACE: PROTEOMIC ANALYSIS OF THE SURFACEOME IN HUMAN PIGMENT CELLS | |
| P-169 | Éva Klement ION MOBILITY FOR IN-DEPTH PROTEOMICS OF COMPLEX BIOLOGICAL SAMPLES | |
| P-170 | Barbara Borsos Monitoring breast cancer-related qPCR-based miRNA profile | |
| P-171 | Luca Gál Regulation of alternative splicing in connection with intronic miRNA maturation pathways | |
| P-172 | Ilona Csordás Ionizing radiation effect on the miRNA cargo of extracellular vesicles | |
| P-173 | Anita Schamberger Examination of artificial mirtrons designed to silence the ABCG2 multidrug transporter protein | |
| P-174 | Zsuzsanna Biczók Allele-specific editing of stem cell models carrying autosomal dominant mutations using the CRISPR/Cas system | |
| P-175 | Anshu Sharma EFFECT OF DOXORUBICIN ON RAR MOBILITY AND CHROMATIN BINDING | |
| P-176 | Chinzorig Jeppesen EGF BINDING TO ITS RECEPTOR OCCURS ALREADY IN THE GOLGI | |
| P-177 | Boglárka Bozsó Intracellular ligand binding of the IL-2 receptor | |
| P-178 | Tamás Maruzs Exploring Sorting nexin functions in Drosophila | |
| P-179 | Bálint Biró Mitochondrial insertions in the rabbit nuclear genome | |
| P-180 | Zsuzsa Szondy TAM KINASE SIGNALING IS INDISPENSABLE FOR PROPER SKELETAL MUSCLE REGENERATION IN MICE | |
| P-181 | Kinga Fedor-Lénárt Tissue transglutaminase knock-out preadipocytes and beige cells of epidydimal fat origin possess decreased mitochondrial functions required for thermogenesis | |
| P-182 | Abhirup Shaw BMP7 upregulates both UCP1 dependent and independent thermogenesis in human neck area derived adipocytes | |
| P-183 | Eszter Németh Prospectively-defined patterns of APOBEC3A mutagenesis are prevalent in human cancers | |
| P-184 | Angéla Békési Getting mechanistic insight into the action of thymidylate synthase inhibitory drugs | |
| P-185 | Rosevalentine Bosire ACCESSIBILITY OF DNA IN CHROMATIN: THE INFLUENCE OF CONSTRAINED SUPERHELICITY | |
| P-186 | Ferenc Jankovics Drosophila small ovary gene is required for transposon silencing and heterochromatin organization | |
| P-187 | Noémi Borbély Towards building the genetic map of the Carpathian Basin | |
| P-188 | Rini Arianti ASC-1 transporter-dependent amino acid uptake is required for the efficient thermogenic response of human adipocytes to adrenergic stimulation | |
| P-189 | Beáta B. Tóth Regulatory Modules of Human Thermogenic Adipocytes: Functional Genomics of Large Cohort and Meta-Analysis Derived Marker-Genes | |
| P-190 | Bálint Péterfia Natural point mutations of the PDZ domain affect ligand binding of the postsynaptic Shank1 protein | |
| P-191 | Flóra Szeri Plasma inorganic pyrophosphate level decreases in pregnancy resulting in elevated Cardiovascular Disease Risk in women giving multiple childbirths | |